Review-Recent Advances in Electrochemical Chiral Recognition
Review-Recent Advances in Electrochemical Chiral Recognition
复制标题
电化学手性识别最新进展综述
DOI：
10.1149/2.1121906jes
复制
发表时间：
2019
影响因子：
3.9
通讯作者：
Wong Kwok yin
中科院分区：
文献类型：
--
作者：
Zhu Gangbing;Kingsford Odoom Jibrael;Yi Yinnhui;Wong Kwok yin
手性在化学和生物学研究中具有重要的影响，因为大多数活性物质都具有手性。通常，手性对映体的性能和性质在生化活性、毒性、转运机制和代谢途径方面表现出显著的差异。因此，开发有效的手性识别方法具有重要意义，一直是化学/生物学研究的热点。近年来，电化学技术在手性识别中的应用受到了广泛的关注。本文综述了近5年来电化学手性识别的研究进展。最后，对电化学手性识别领域的一些关键问题和展望进行了讨论。
Chirality has an important impact in chemical and biological research, since most active substances possess chirality. Usually, the performance and properties of chiral enantiomers exhibit significant differences in terms of biochemical activity, toxicity, transport mechanism and pathways of metabolism. Thus, developing effective method to achieve chiral recognition is of great significance and has always been a hot topic in chemo/biological study. In recent years, the electrochemical technologies, which can offer many advantages over the other conventional methods, have received considerable attention in chiral recognition. In this review, a comprehensive and critical detail of the trends on electrochemical chiral recognition in the last 5 years have been presented. In addition, some critical challenges and prospects in the field of electrochemical chiral recognition are also discussed in the latter part.