Eosinophilic gastrointestinal disorders in infants : a Japanese case series

Eosinophilic gastrointestinal disorders in infants : a Japanese case series
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婴儿嗜酸性胃肠道疾病:日本病例系列

DOI:
10.1159/000327264
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发表时间:
2011
期刊:
Int Arch Allergy Immunol
影响因子:
--
通讯作者:
et al
et al
中科院分区:
--
文献类型:
--
作者:
Yamada Y;et al

文献摘要

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研究背景嗜酸性粒细胞性胃肠疾病(EGIDs)是以胃肠道原发性嗜酸性粒细胞炎症为特征的疾病.有少数报告称,婴儿胃肠道中的嗜酸性粒细胞浸润表现为EGID。在这项研究中,我们提出了日本的EGIDs在infants.MethodsFive例诊断或强烈怀疑有EGIDs在我院从2008年至2010年进行了审查。在4和3 patients.ResultsThere进行放射性造影剂灌肠检查和/或内镜检查,分别与嗜酸性粒细胞性结肠炎(1怀疑和2活检证实),一个病人谁被怀疑有过敏性嗜酸性粒细胞性小肠结肠炎,和嗜酸性粒细胞性胃肠炎与小儿嗜酸性粒细胞增多syndrome.ConclusionsThe原因和临床表现的患者肠道嗜酸性粒细胞炎症各不相同。因此,仔细检查和观察对于婴儿EGID患者很重要。
BackgroundEosinophilic gastrointestinal disorders (EGIDs) are disorders characterized by primary eosinophil inflammation in the gastrointestinal tract. There are a small number of reports of eosinophil infiltration in gastrointestinal tracts presenting as EGIDs in infants. In this study, we present Japanese cases of EGIDs in infants.MethodsFive patients diagnosed with or strongly suspected to have EGIDs in our hospital from 2008 to 2010 were reviewed. Radiographic contrast enema examinations and/or endoscopies were performed in 4 and 3 patients, respectively.ResultsThere were patients with eosinophilic colitis (1 suspected and 2 biopsy-proven), a patient who was suspected of having allergic eosinophilic enterocolitis, and a patient with eosinophilic gastroenteritis associated with pediatric hypereosinophilic syndrome.ConclusionsThe causes and clinical findings of patients with intestinal eosinophil inflammation vary. Therefore, deliberate examination and observation are important for patients with infantile EGID.