The Level of Cortical Afferent Inhibition in Acute Stroke Correlates With Long-Term Functional Recovery in Humans
The Level of Cortical Afferent Inhibition in Acute Stroke Correlates With Long-Term Functional Recovery in Humans
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DOI：
10.1161/strokeaha.111.631085
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发表时间：
2012-01-01
期刊：
影响因子：
8.3
通讯作者：
Dileone, Michele
中科院分区：
文献类型：
--
作者：
Di Lazzaro, Vincenzo;Profice, Paolo;Dileone, Michele
背景与目的——我们利用经颅磁刺激技术，研究了急性缺血性脑卒中的短间隔皮质内抑制和短潜伏期传入抑制。
方法——我们对16例患者的患侧半球和健侧半球的短间隔皮质内抑制和短潜伏期传入抑制进行了评估，并将电生理参数与6个月时的预后相关联。
结果——患者患侧半球的短潜伏期传入抑制显著降低，且短潜伏期传入抑制水平与功能预后相关。
结论——急性脑卒中传入抑制的降低与长期恢复相关。（《卒中》2012年；43卷：250 - 252页）
Background and Purpose-Using transcranial magnetic stimulation, we investigated short-interval intracortical inhibition and short-latency afferent inhibition in acute ischemic stroke.Methods-We evaluated short-interval intracortical inhibition and short-latency afferent inhibition in the affected hemisphere and unaffected hemisphere in 16 patients and correlated electrophysiological parameters with outcome at 6 months.Results-Affected hemisphere short-latency afferent inhibition was significantly reduced in patients, and short-latency afferent inhibition level correlated with functional outcome.Conclusions-Reduced afferent inhibition in acute stroke correlates with long-term recovery. (Stroke. 2012;43:250-252.)