Surgery Combined with Radiotherapy to Treat Spinal Tumors: A Review of Published Reports
Surgery Combined with Radiotherapy to Treat Spinal Tumors: A Review of Published Reports
复制标题
手术联合放射治疗治疗脊柱肿瘤：已发表报告的回顾
DOI：
10.1111/os.12230
复制
发表时间：
2016-05
影响因子：
2.1
通讯作者：
Dong Jian
中科院分区：
文献类型：
--
作者：
Bian Chong;Chen Nong;Li Xi lei;Zhou Xiao gang;Lin Hong;Jiang Li bo;Liu Wang mi;Chen Qian;Dong Jian
脊柱肿瘤发病率高，肢体瘫痪发生率高。手术治疗和放射治疗(RT)都被用来治疗脊柱肿瘤，然而，如何最好地结合这两种治疗方法以最大限度地提高益处和最大限度地减少风险仍存在争议。也很难决定RT的最佳时机、疗程和剂量，特别是对孕妇和儿童。本综述的目的是通过提供有关更精确和更安全地实施RT的先进技术的综合信息，以及关于手术和RT相结合的各种方法对治疗结果的影响，来帮助正在处理脊柱肿瘤的外科医生。我们在这里回顾已发表的关于联合使用这两种治疗方法治疗脊柱肿瘤的报道，并试图就最佳治疗方案的选择得出适当的结论。我们的结论是，术后放射治疗，特别是高精度、低剂量、多分割的放射治疗，以及近距离放射治疗是很有希望结合手术的治疗方法。
Spinal tumors result in high morbidity and a high rate of lower limb paralysis. Both surgical therapy and radiation therapy (RT) are used to treat spinal tumors; however, how best to combine these two therapies to maximize the benefits and minimize the risks is still being debated. It is also difficult to decide the optimal timing, course and dose of RT, especially in pregnant women and children. The aim of this review is to assist surgeons who are dealing with spinal tumors by providing comprehensive information about advanced techniques for administering RT with greater precision and safety, and about the impact of various ways of combining surgery and RT on therapeutic outcomes. We here review published reports about treating spinal tumors with a combination of these two forms of therapy and attempt to draw appropriate conclusions concerning selection of optimal treatment protocols. Our conclusion is that postoperative radiotherapy, especially with high‐precision, low‐dose and multiple fractions, and brachytherapy are promising therapies to combined with surgery.
登录
查看更多内容
影响因子：
2.7
作者：
M. Chandy;S. Babu
通讯作者：
M. Chandy;S. Babu
DOI：
10.1097/spc.0b013e32830c9060
发表时间：
2008-09
影响因子：
2.1
作者：
K. Siemionow;I. Lieberman
通讯作者：
K. Siemionow;I. Lieberman
影响因子：
3.8
作者：
N. Kanematsu;Y. Koba;R. Ogata;T. Himukai
通讯作者：
N. Kanematsu;Y. Koba;R. Ogata;T. Himukai
DOI：
10.1186/1748-717x-9-69
发表时间：
2014-03-04
期刊：
Radiation oncology (London, England)
影响因子：
--
作者：
Fisher CG;Schouten R;Versteeg AL;Boriani S;Varga PP;Rhines LD;Kawahara N;Fourney D;Weir L;Reynolds JJ;Sahgal A;Fehlings MG;Gokaslan ZL
通讯作者：
Gokaslan ZL
影响因子：
2.8
作者：
Clarke, Michelle J.;Zadnik, Patricia L.;Wolinsky, Jean-Paul
通讯作者：
Wolinsky, Jean-Paul