Comparison of the natural history of alcoholic and nonalcoholic fatty liver disease.
Comparison of the natural history of alcoholic and nonalcoholic fatty liver disease.
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DOI：
10.1007/s11894-005-0063-4
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发表时间：
2005-02-01
影响因子：
--
通讯作者：
Harrison, Stephen A
中科院分区：
文献类型：
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作者：
Mills, Shane J;Harrison, Stephen A
脂肪肝是一种常见的临床疾病。它被经典地分为酒精性脂肪性肝病（AFLD）和非酒精性脂肪性肝病（NAFLD）。虽然AFLD发生在多达1000万美国人中，但NAFLD是最常见的慢性肝病，也是美国肝酶异常的最常见原因。这两种疾病都包括脂肪变性、脂肪性肝炎和肝硬化的临床谱。虽然它们在组织学上是模糊的，但AFLD和NAFLD遵循不同的临床过程。本文比较了这些疾病的自然史。
Fatty liver disease represents a common clinical entity. It is classically divided into alcoholic fatty liver disease (AFLD) and nonalcoholic fatty liver disease (NAFLD). Whereas AFLD occurs in as many as 10 million Americans, NAFLD represents the most common chronic liver disease and is the most common cause of liver enzyme abnormalities in the United States. Both diseases encompass the clinical spectrum of steatosis, steatohepatitis, and cirrhosis. Although they are histologically indistinct, AFLD and NAFLD follow different clinical courses. This article compares the natural history of these diseases.