An operational definition of epigenetics
An operational definition of epigenetics
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DOI：
10.1101/gad.1787609
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发表时间：
2009-04-01
影响因子：
10.5
通讯作者：
Shilatifard, Ali
中科院分区：
文献类型：
--
作者：
Berger, Shelley L.;Kouzarides, Tony;Shilatifard, Ali
最近（2008年12月），班伯里会议中心和冷泉港实验室主办了一次关于基于染色质的表观遗传学的会议。其目的是讨论基因组功能的表观遗传控制的各个方面，并达成一个共识的“表观遗传学”的定义，以供更广泛的社区考虑。很明显，多个机械步骤导致表观遗传表型的稳定遗传。以下是我们对会议进程的看法和解释。
A recent meeting (December 2008) regarding chromatin-based epigenetics was hosted by the Banbury Conference Center and Cold Spring Harbor Laboratory. The intent was to discuss aspects of epigenetic control of genomic function, and to arrive at a consensus definition of "epigenetics'' to be considered by the broader community. It was evident that multiple mechanistic steps lead to the stable heritance of the epigenetic phenotype. Below we provide our view and interpretation of the proceedings at the meeting.