Post-genomic science: cross-disciplinary and large-scale collaborative research and its organizational and technological challenges for the scientific research process
Post-genomic science: cross-disciplinary and large-scale collaborative research and its organizational and technological challenges for the scientific research process
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DOI：
10.1098/rsta.2006.1785
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发表时间：
2006-06-15
期刊：
影响因子：
5
通讯作者：
Gavaghan, David
中科院分区：
文献类型：
--
作者：
Welsh, Elaine;Jirotka, Marina;Gavaghan, David
我们研究了跨学科科学的最新发展，并认为“大科学”的方法在生命科学中越来越明显，这是由学科之间的传统障碍和跨这些学科的技术应用的打破所促成的。“大生物学”的第一批成果开始出现在基因组学、（生物）纳米技术和系统生物学等领域。我们认为，这对研究过程产生了深远的影响，并在技术设计，提供基础设施和培训，组织研究小组，并提供适当的研究资金机制和奖励制度提出了挑战。如果要充分实现这一办法的承诺，就必须应对这些挑战。在本文中，我们将借鉴社会科学家的工作，以了解这些科学和技术的发展如何与组织文化，组织变革和科学工作的背景。我们试图从以前的技术发展中学习，这些技术发展似乎为组织和社会变革提供了类似的潜力。
We examine recent developments in cross-disciplinary science and contend that a 'Big Science' approach is increasingly evident in the life sciences-facilitated by a breakdown of the traditional barriers between academic disciplines and the application of technologies across these disciplines. The first fruits of 'Big Biology' are beginning to be seen in, for example, genomics, (bio)-nanotechnology and systems biology. We suggest that this has profound implications for the research process and presents challenges both in technological design, in the provision of infrastructure and training, in the organization of research groups, and in providing suitable research funding mechanisms and reward systems. These challenges need to be addressed if the promise of this approach is to be fully realized. In this paper, we will draw on the work of social scientists to understand how these developments in science and technology relate to organizational culture, organizational change and the context of scientific work. We seek to learn from previous technological developments that seemed to offer similar potential for organizational and social change.