Thrombocytopenia and prognosis in intensive care
Thrombocytopenia and prognosis in intensive care
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DOI：
10.1097/00003246-200006000-00031
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发表时间：
2000-06-01
影响因子：
8.8
通讯作者：
Bobbaers, H
中科院分区：
文献类型：
--
作者：
Vanderschueren, S;De Weerdt, A;Bobbaers, H
目的：研究成人重症监护病房(ICU)患者血小板减少的发生率和预后。设计：前瞻性观察队列研究。设置：一所大学医院的内科ICU和一所地区医院的内科ICU和一所地区医院的内外科联合ICU。患者：所有患者在5个月内连续入院。干预：患者监测和数据收集。测量和主要结果：主要结局指标为ICU死亡率。对329例患者的资料进行分析。ICU总死亡率为19.5%。总共有136名患者(41.3%)至少有一次血小板计数为150x10(9)/L(P<；所有比较均为0.0005)。非血小板计数在101×10(9)/L和149×10(9)/L之间的出血发生率从4.1%上升到52.6%(p=0.002)。
Objective: To study the incidence and prognosis of thrombocytopenia in adult intensive care unit (ICU) patients.Design: Prospective observational cohort study.Setting: The medical ICU of a university hospital and the combined medical-surgical ICU of a regional hospital.Patients: All patients consecutively admitted during a 5-month period.Interventions: Patient surveillance and data collection.Measurements and Main Results:The primary outcome measure was ICU mortality. Data of 329 patients were analyzed. Overall ICU mortality rate was 19.5%. A total of 136 patients (41.3%) had at least one platelet count 150 x 10(9)/L (p < .0005 for all comparisons). Bleeding incidence rose from 4.1% in non-platelet counts between 101 x 10(9)/L and 149 x 10(9)/L (p = .0002) and to 52.6% in patients with minimal platelet counts