Antifungal activity of silver nanoparticles on some of fungi
Antifungal activity of silver nanoparticles on some of fungi
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DOI：
10.7508/ijnd.2010.03.007
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发表时间：
2011-12-01
影响因子：
1.5
通讯作者：
Mansourkiaee, P.
中科院分区：
文献类型：
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作者：
Nasrollahi, A.;Pourshamsian, Kh.;Mansourkiaee, P.
本研究探讨了银纳米粒子（Ag-Nps）对白色念珠菌（ATCC 5027）、酿酒酵母（ATCC 5027）的抗真菌作用。采用最小抑菌浓度（MIC）法，研究了两性霉素B、氟康唑及合成的银纳米粒子对真菌的作用，并通过扫描电镜（SEM）观察了其对酵母细胞膜反应的影响。本研究结果表明，银纳米粒子与其他抗真菌药物相比具有相当的抗真菌活性，值得进一步研究以供临床应用。
In this study, we investigated the antifungal effects of silver nanoparticles (Ag-Nps) on Candida albicans (ATCC 5027), Saccharomyces cerevisiae (ATCC 5027). Investigating method by using Minimum Inhibitory Concentration (MIC) technique, some of drugs including Amphotericin B, Fluconazole and synthesized Ag-Nps have been obtained on the fungi and the changes on membrane reactions of yeasts have been elucidated by Scanning Electron Microscopy (SEM). The present study indicates Ag-Nps has considerable antifungal activity comparison with other antifungal drugs, so deserving further investigation for clinical applications.