Do drug samples influence resident prescribing behavior? A randomized trial
Do drug samples influence resident prescribing behavior? A randomized trial
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DOI：
10.1016/j.amjmed.2005.02.031
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发表时间：
2005-08-01
影响因子：
5.9
通讯作者：
Holmgren, LR
中科院分区：
文献类型：
--
作者：
Adair, RF;Holmgren, LR
目的：本研究的目的是确定获取药物样本是否会影响住院医生的处方决策。 对象和方法：作者观察了 29 名内科住院医师在 6 个月内在市中心一家初级保健诊所做出的 390 项开始药物治疗的决定。通过随机选择，一半的居民同意不使用现有的免费药物样品。选择五种药物对进行前瞻性研究。高度广告的药物与通常用于相同适应症、价格较低、可在柜台购买或提供仿制药的药物相匹配。 结果：与无法获得样品的住院医生（138/188 决定；P=.04）相比，能够获得药物样本的住院医师选择未广告药物的可能性较小（131/202 决定；P=.04），并且不太可能选择非处方药物（51/202、73/188；P=0.04）。 P=.003)。廉价药物的使用呈减少趋势。结论：在诊所获取药物样本会影响住院医师的处方决策。这可能会影响住院医师教育并增加患者的药品费用。 (C) 2005 Elsevier Inc. 保留所有权利。
Purpose: The purpose of the study was to determine whether access to drug samples influences resident prescribing decisions.Subjects and Methods: The authors observed 390 decisions to initiate drug therapy by 29 internal medicine residents over a 6-month period in an inner-city primary care clinic. By random selection, half of the residents agreed not to use available free drug samples. Five drug class pairs were chosen for study prospectively. Highly advertised drugs were matched with drugs commonly used for the same indication that were less expensive, available over-the-counter, or available in generic formulation.Results: Resident physicians with access to drug samples were less likely to choose unadvertised drugs (131/202 decisions) than residents who did not have access to samples (138/188 decisions; P=.04) and less likely to choose over-the-counter drugs (51/202, 73/188; P=.003). There was a trend toward less use of inexpensive drugs.Conclusion: Access to drug samples in clinic influences resident prescribing decisions. This could affect resident education and increase drug costs for patients. (C) 2005 Elsevier Inc. All rights reserved.