Solution NMR structure of Alr2454 from Nostoc sp. PCC 7120, the first structural representative of Pfam domain family PF11267.
Solution NMR structure of Alr2454 from Nostoc sp. PCC 7120, the first structural representative of Pfam domain family PF11267.
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DOI：
10.1007/s10969-012-9135-5
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发表时间：
2012-09
期刊：
影响因子：
--
通讯作者：
Montelione, Gaetano T
中科院分区：
文献类型：
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作者：
Aramini, James M;Petrey, Donald;Lee, Dong Yup;Janjua, Haleema;Xiao, Rong;Acton, Thomas B;Everett, John K;Montelione, Gaetano T
蛋白质结构域家族PF 11267（DUF 3067）是在细菌和真核生物中发现的功能未知的蛋白质家族。在这里，我们提出的102-残基Alr 2454蛋白质的溶液NMR结构从念珠藻属PCC 7120，这构成了第一个结构代表从这个保守的蛋白质结构域家族。Nostoc sp.Alr2454的结构采用了一种新的蛋白质折叠。
Protein domain family PF11267 (DUF3067) is a family of proteins of unknown function found in both bacteria and eukaryotes. Here we present the solution NMR structure of the 102-residue Alr2454 protein from Nostoc sp. PCC 7120, which constitutes the first structural representative from this conserved protein domain family. The structure of Nostoc sp. Alr2454 adopts a novel protein fold.