Mapper: an intelligent restriction mapping tool.
Mapper: an intelligent restriction mapping tool.
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Mapper：智能限制映射工具。
DOI：
10.1093/bioinformatics/14.2.101
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发表时间：
1998
期刊：
影响因子：
--
通讯作者：
Zou,Y
中科院分区：
文献类型：
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作者：
Inglehart,JA;Nelson,PC;Zou,Y
动机：确定用于自动限制图的最强大的人工智能技术，并使用它们创建强大的多酶限制图工具。结果：最有效的搜索引擎使用了模型驱动的穷举搜索和基于普拉特分离理论的二进制逻辑剪枝。通过进一步的试验，开发了显著加快搜索速度的输入预处理模块和使用户能够分析大型解集并降低其明显复杂性的输出后处理模块。可用性：生成的工具Mapper的可执行版本可从我们的网站(http://www.ai.eecs.uic.edu))下载，方法是选择“软件”选项。联系人：nelson@eecs.uic.edu(http://www.ai.eecs.uic.edu/√±elson)
MOTIVATION: To determine the most powerful artificial intelligence techniques for automated restriction mapping, and use them to create a powerful multiple-enzyme restriction mapping tool. RESULTS: The most effective search engine utilized model-driven exhaustive search and a form of binary logic pruning based on Pratt's separation theory. Additional experimentation led to the development of an input preprocessing module which significantly speeds up searches, and an output post-processing module which enables users to analyze large solution sets and reduce their apparent complexity. AVAILABILITY: An executable version of the resultant tool, Mapper, can be downloaded from our Web site (http://www.ai.eecs.uic.edu) by selecting the 'Software' option. CONTACT: nelson@eecs.uic.edu (http://www.ai.eecs.uic.edu/ñelson).