Stability of multiple-locus variable-number tandem repeats in Salmonella enterica serovar Typhimurium
Stability of multiple-locus variable-number tandem repeats in Salmonella enterica serovar Typhimurium
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DOI：
10.1128/jcm.00715-07
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发表时间：
2007-09-01
影响因子：
9.4
通讯作者：
Threlfall, E. J.
中科院分区：
文献类型：
--
作者：
Hopkins, K. L.;Maguire, C.;Threlfall, E. J.
可变数目串联重复序列 (VNTR) 可能进化得如此之快，以至于在爆发期间会出现多种特征。通过脉冲场凝胶电泳和 VNTR 分型分析了来自 8 次鼠伤寒沙门氏菌暴发的总共 190 个分离株和来自 7 名患者的 15 个分离株。注意到基因座的微小变化；除此之外，VNTR 谱在疫情爆发期间保持稳定。
Variable-number tandem repeats (VNTRs) may evolve so rapidly that multiple profiles emerge during an outbreak. A total of 190 isolates from eight Salmonella enterica serovar Typhimurium outbreaks and 15 isolates from seven patients were analyzed by pulsed-field gel electrophoresis and VNTR typing. Small changes in loci were noted; otherwise, the VNTR profiles were stable during the course of the outbreaks.