Seroreactivity and Risk Factors Associated with Coxiella burnetii Infection among Cattle Slaughterhouse Workers in South Korea
Seroreactivity and Risk Factors Associated with Coxiella burnetii Infection among Cattle Slaughterhouse Workers in South Korea
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DOI：
10.3390/ijerph15102264
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发表时间：
2018-10-01
影响因子：
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通讯作者：
Lee, Kwan
中科院分区：
文献类型：
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作者：
Park, Ji-Hyuk;Hwang, Seon Do;Lee, Kwan
Q热由贝氏柯克斯体引起，是一种人畜共患疾病，对与动物或其尸体密切接触的工作人员来说是一种职业危害。一项全国性的血清学研究在牛屠宰场工人中进行，这些工人被认为有感染C。在韩国进行贝氏体感染以研究C.贝氏体感染并确定相关危险因素。在韩国的1017名牛屠宰场工人中，有923名（90.8%）参与了这项横断面研究。检测样本中的免疫球蛋白G（IgG）和M（IgM）抗体，以对抗II C期。间接免疫荧光法检测贝氏体。总体血清反应性（定义为IgG或IgM抗体滴度临界值1：16）为9.1%（84/923）。此外，还发现C.在多变量分析中，贝氏体感染和执行胴体内脏取出工作（比值比，2.36; 95%置信区间，1.39-4.03）。减少C.由于伯内特氏菌感染，牛屠宰场工作人员需要在内脏取出过程中采取预防措施。
Q fever, caused by Coxiella burnetii, is a zoonotic disease that is an occupational hazard to people who work in close contact with animals or their carcasses. A nationwide serologic study among cattle slaughterhouse workers who were presumed to be at risk of having C. burnetii infection in South Korea was performed to investigate the seroreactivity of C. burnetii infection and identify related risk factors. Out of 1017 cattle slaughterhouse workers in South Korea, 923 (90.8%) participated in this cross-sectional study. Samples were tested for immunoglobulin G (IgG) and M (IgM) antibodies against phase II C. burnetii via indirect immunofluorescence assay. The overall seroreactivity, defined as IgG or IgM antibody titer cutoffs 1:16, was 9.1% (84/923). Additionally, a significant association was found between the seroreactivity of C. burnetii infection and performing carcass evisceration work (odds ratio, 2.36; 95% confidence interval, 1.39-4.03) in multivariate analysis. To diminish C. burnetii infection, cattle slaughterhouse workers need to take precautions during the evisceration process.