Histomorphometric analysis of normal bone from the iliac crest of Norwegian subjects.
Histomorphometric analysis of normal bone from the iliac crest of Norwegian subjects.
复制标题
挪威受试者髂嵴正常骨的组织形态计量学分析。
DOI：
--
复制
发表时间：
1988
期刊：
影响因子：
--
通讯作者：
A. Attramadal
中科院分区：
文献类型：
--
作者：
E. Dahl;K. Nordal;J. Halse;A. Attramadal
从72名21-81岁的健康挪威人（46名女性）中获得经髂骨骨活检。22名男性和40名女性使用四环素进行双标记。通过点计数和简单测量对未脱钙切片进行组织形态学分析，以确定挪威人群的正常平均值和范围。所获得的数据与其他欧洲研究所披露的数据吻合得很好。在男性中，类骨质表面与侵蚀表面相关，但在女性中不相关。男性的所有骨测量值均与年龄无关。在女性中，除贴壁率外，所有测量的骨形成指数均随年龄增长而增加，而平均皮质厚度和松质骨体积则随年龄增长而减少。女性表面骨形成率也随年龄增长而增加。男性的类骨质和标记表面以及骨形成率的平均值较高。与其他报告的偏离可能是由于本研究中年龄分布不同，老年人较多。
Transiliac bone biopsies were obtained from 72 healthy Norwegians (46 women) aged 21-81 years. Twenty-two men and 40 women were double-labelled with tetracycline. Histomorphometric analysis was done on undecalcified sections by means of point counting and simple measurements in order to establish normal mean values and ranges in a Norwegian population. The data obtained correspond well with those disclosed by other European studies. Osteoid surface was correlated with eroded surface in men but not in women. All bone measurements were independent of age in men. In women, all measured formation indices except apposition rate increased, while mean cortical thickness and cancellous bone volume decreased with age. Surface based bone formation rate also increased with age in women. Mean values for osteoid and labelled surfaces as well as bone formation rate were higher in men. The deviation from other reports may be due to a different age distribution with more older people in the present study.