Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
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DOI：
10.1038/s41418-017-0012-4
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发表时间：
2018-03
影响因子：
12.4
通讯作者：
Kroemer G
中科院分区：
文献类型：
--
作者：
Galluzzi L;Vitale I;Aaronson SA;Abrams JM;Adam D;Agostinis P;Alnemri ES;Altucci L;Amelio I;Andrews DW;Annicchiarico-Petruzzelli M;Antonov AV;Arama E;Baehrecke EH;Barlev NA;Bazan NG;Bernassola F;Bertrand MJM;Bianchi K;Blagosklonny MV;Blomgren K;Borner C;Boya P;Brenner C;Campanella M;Candi E;Carmona-Gutierrez D;Cecconi F;Chan FK;Chandel NS;Cheng EH;Chipuk JE;Cidlowski JA;Ciechanover A;Cohen GM;Conrad M;Cubillos-Ruiz JR;Czabotar PE;D'Angiolella V;Dawson TM;Dawson VL;De Laurenzi V;De Maria R;Debatin KM;DeBerardinis RJ;Deshmukh M;Di Daniele N;Di Virgilio F;Dixit VM;Dixon SJ;Duckett CS;Dynlacht BD;El-Deiry WS;Elrod JW;Fimia GM;Fulda S;García-Sáez AJ;Garg AD;Garrido C;Gavathiotis E;Golstein P;Gottlieb E;Green DR;Greene LA;Gronemeyer H;Gross A;Hajnoczky G;Hardwick JM;Harris IS;Hengartner MO;Hetz C;Ichijo H;Jäättelä M;Joseph B;Jost PJ;Juin PP;Kaiser WJ;Karin M;Kaufmann T;Kepp O;Kimchi A;Kitsis RN;Klionsky DJ;Knight RA;Kumar S;Lee SW;Lemasters JJ;Levine B;Linkermann A;Lipton SA;Lockshin RA;López-Otín C;Lowe SW;Luedde T;Lugli E;MacFarlane M;Madeo F;Malewicz M;Malorni W;Manic G;Marine JC;Martin SJ;Martinou JC;Medema JP;Mehlen P;Meier P;Melino S;Miao EA;Molkentin JD;Moll UM;Muñoz-Pinedo C;Nagata S;Nuñez G;Oberst A;Oren M;Overholtzer M;Pagano M;Panaretakis T;Pasparakis M;Penninger JM;Pereira DM;Pervaiz S;Peter ME;Piacentini M;Pinton P;Prehn JHM;Puthalakath H;Rabinovich GA;Rehm M;Rizzuto R;Rodrigues CMP;Rubinsztein DC;Rudel T;Ryan KM;Sayan E;Scorrano L;Shao F;Shi Y;Silke J;Simon HU;Sistigu A;Stockwell BR;Strasser A;Szabadkai G;Tait SWG;Tang D;Tavernarakis N;Thorburn A;Tsujimoto Y;Turk B;Vanden Berghe T;Vandenabeele P;Vander Heiden MG;Villunger A;Virgin HW;Vousden KH;Vucic D;Wagner EF;Walczak H;Wallach D;Wang Y;Wells JA;Wood W;Yuan J;Zakeri Z;Zhivotovsky B;Zitvogel L;Melino G;Kroemer G
在过去的十年里，细胞死亡命名委员会制定了从形态、生化和功能角度对细胞死亡进行定义和解释的指南。随着这一领域的不断扩大和协调多个细胞死亡途径的新机制的公布，我们提出了一个更新的细胞死亡子程序分类，重点放在该过程的机械性和基本(而不是相关和可有可无的)方面。由于我们提供了面向分子的术语定义，包括内源性细胞凋亡、外源性细胞凋亡、线粒体通透性转变(MPT)导致的坏死、坏死性下垂、铁性下垂、色素下垂、死胎、内生细胞死亡、NETotic细胞死亡、溶酶体依赖细胞死亡、自噬依赖细胞死亡、免疫原性细胞死亡、细胞衰老和有丝分裂灾难，我们讨论了指这些过程的高度专门化实例的新词的用途。NCD的任务是提供一个被广泛接受的细胞死亡命名法，以支持该领域的持续发展。
Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemical, and functional perspectives. Since the field continues to expand and novel mechanisms that orchestrate multiple cell death pathways are unveiled, we propose an updated classification of cell death subroutines focusing on mechanistic and essential (as opposed to correlative and dispensable) aspects of the process. As we provide molecularly oriented definitions of terms including intrinsic apoptosis, extrinsic apoptosis, mitochondrial permeability transition (MPT)-driven necrosis, necroptosis, ferroptosis, pyroptosis, parthanatos, entotic cell death, NETotic cell death, lysosome-dependent cell death, autophagy-dependent cell death, immunogenic cell death, cellular senescence, and mitotic catastrophe, we discuss the utility of neologisms that refer to highly specialized instances of these processes. The mission of the NCCD is to provide a widely accepted nomenclature on cell death in support of the continued development of the field.
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影响因子：
21.3
作者：
Alanko J;Mai A;Jacquemet G;Schauer K;Kaukonen R;Saari M;Goud B;Ivaska J
通讯作者：
Ivaska J
影响因子：
19
作者：
Aouacheria A;Rech de Laval V;Combet C;Hardwick JM
通讯作者：
Hardwick JM
影响因子：
21.3
作者：
通讯作者：
--
影响因子：
13.8
作者：
Aouacheria, Abdel;Combet, Christophe;Tompa, Peter;Hardwick, J. Marie
通讯作者：
Hardwick, J. Marie
影响因子：
12.4
作者：
Amelio I;Melino G;Frezza C
通讯作者：
Frezza C