The Importance of Nutrition in the Prevention of Ocular Disease with Special Reference to Cataract
The Importance of Nutrition in the Prevention of Ocular Disease with Special Reference to Cataract
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DOI：
10.1159/000316477
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发表时间：
2010-01-01
影响因子：
2.1
通讯作者：
Tarwadi, Kirtan
中科院分区：
文献类型：
--
作者：
Agte, Vaishali;Tarwadi, Kirtan
背景：透镜是最易受到氧化损伤的眼部结构。抗氧化剂，微量营养素和植物化学物质已被广泛研究，以预防或延缓各种眼部疾病的进展。目的：简要概述了抗氧化剂和微量营养素在预防和治疗眼部疾病中的作用的最新文献，重点介绍了白内障。数据来源：Pub-Med检索和期刊中的个别论文。数据综合：该综述讨论了各种微量营养素和抗氧化剂以及氧化应激与白内障的联系。饮食干预作为预防白内障和其他眼部疾病的策略也进行了审查。结论：食用食物中的抗氧化剂，如β-胡萝卜素、叶黄素和玉米黄质，似乎对治疗黄斑变性和白内障有用。补充维生素A、维生素C、维生素E和锌可能只在高风险个体中预防晚期年龄相关性黄斑变性。版权所有（C）2010 S. Karger AG，巴塞尔
Background: The lens is the ocular structure most susceptible to oxidative damage. Antioxidants, micronutrients and phytochemicals have been extensively studied for their possible effects to prevent or delay the progression of various eye diseases. Objectives: A brief overview of the updated literature on the role of antioxidants and micronutrients in the prevention and treatment of ocular diseases is to be presented with an emphasis on cataract. Data Sources: Pub-Med search and individual papers from journals. Data Synthesis: The review discusses linkages of various micronutrients and antioxidants as well as oxidative stress with cataract. Dietary interventions as strategy for prevention of cataract and other ocular disorders are also reviewed. Conclusions: Consumption of food-based antioxidants like beta-carotene lutein and zeaxanthin seem to be useful for the treatment of macular degeneration and cataracts. Supplements of vitamin A, vitamin C, vitamin E and zinc may prevent advanced age-related macular degeneration only in high-risk individuals. Copyright (C) 2010 S. Karger AG, Basel