POSSIBLE FUNCTIONS OF TUMOR-ASSOCIATED CARBOHYDRATE ANTIGENS
POSSIBLE FUNCTIONS OF TUMOR-ASSOCIATED CARBOHYDRATE ANTIGENS
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DOI：
10.1016/0952-7915(91)90091-e
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发表时间：
1991-10-01
影响因子：
7
通讯作者：
HAKOMORI, S
中科院分区：
文献类型：
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作者：
HAKOMORI, S
一些肿瘤相关糖抗原的表达可以确定肿瘤进展的阶段、速率和表型，并且可能具有预后价值。这些抗原中的一些现在被认为是确定转移部位的粘附分子。肿瘤相关糖抗原的单克隆抗体或抗原本身不仅可以作为经典的免疫学试剂，还可以作为用于预防肿瘤进展的抗粘附试剂。
Expression of some tumor-associated carbohydrate antigens may define the stage, rate and phenotype of tumor progression and may have prognostic value. Some of these antigens are now recognized as adhesion molecules that define the site of metastasis. Monoclonal antibodies to tumor-associated carbohydrate antigens, or the antigens themselves, may serve not only as classic immunological reagents but also as anti-adhesion reagents for the prevention of tumor progression.