Improving Engagement in the HIV Care Cascade: A Systematic Review of Interventions Involving People Living with HIV/AIDS as Peers.
Improving Engagement in the HIV Care Cascade: A Systematic Review of Interventions Involving People Living with HIV/AIDS as Peers.
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DOI：
10.1007/s10461-016-1307-z
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发表时间：
2016-10
影响因子：
4.4
通讯作者：
Operario D
中科院分区：
文献类型：
--
作者：
Genberg BL;Shangani S;Sabatino K;Rachlis B;Wachira J;Braitstein P;Operario D
改善患者对艾滋病毒护理的参与对于最大限度地发挥抗逆转录病毒疗法的影响至关重要。我们对使用HIV阳性同龄人来支持ART的联系、保留和/或依从性的研究进行了系统回顾。我们检索了1996-2014年间在Pubmed、PsycINFO和CINAHL上发表和索引的文章。同龄人必须是艾滋病毒阳性。研究报告仅限于以英文发表的研究报告。9项研究（n= 4，658名受试者）符合纳入标准。基于同行的干预措施主要集中在提高ART的依从性，或通过病毒抑制来评估保留和依从性。5项（56%）是在撒哈拉以南非洲进行的。总体结果是混合的影响，同伴对ART的坚持，病毒抑制和死亡率。虽然发现同伴干预对改善联系和保留的积极影响，但评估这些结果的研究有限。需要进行更多的研究来证明同龄人对不同人群中的联系和保留的影响。
Improving patient engagement in HIV care is critical for maximizing the impact of antiretroviral therapy (ART). We conducted a systematic review of studies that used HIV-positive peers to bolster linkage, retention, and/or adherence to ART. We searched articles published and indexed in Pubmed, PsycINFO, and CINAHL between 1996–2014. Peers were required to be HIV-positive. Studies were restricted to those published in English. Nine studies with n=4,658 participants met the inclusion criteria. Peer-based interventions were predominantly focused on improving adherence to ART, or evaluations of retention and adherence via viral suppression. Five (56%) were conducted in sub-Saharan Africa. Overall findings were mixed on the impact of peers on ART adherence, viral suppression, and mortality. While positive effects of peer interventions on improving linkage and retention were found, there were limited studies assessing these outcomes. Additional research is warranted to demonstrate the impact of peers on linkage and retention in diverse populations.