Interhemispheric asymmetries of the modular structure in human temporal cortex
Interhemispheric asymmetries of the modular structure in human temporal cortex
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DOI：
10.1126/science.289.5486.1946
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发表时间：
2000-09-15
期刊：
影响因子：
56.9
通讯作者：
Singer, W
中科院分区：
文献类型：
--
作者：
Galuske, RAW;Schlote, W;Singer, W
听觉信号的语言相关处理是偏侧的，涉及Brodmann区22的后部。我们发现，这一区域的功能偏侧化伴随着内源性微电路组织的半球间差异。神经束追踪揭示了一个连接规则间隔的神经元簇的远程内在联系的模块化网络。尽管两个半球的星团直径相似，但它们在左半球的间距大约大20%。假设功能和解剖结构之间的关系与视觉皮质相似，目前的数据表明，左侧每个表面单位包含的柱状系统比右侧区域22在功能上更不同。
Language-relevant processing of auditory signals is Lateralized and involve the posterior part of Brodmann area 22. We found that the functional Lateralization in this area was accompanied by interhemispheric differences in the organization of the intrinsic: microcircuitry. Neuronal tract tracing revealed a modular network of long-range intrinsic connections Linking regularly spaced clusters of neurons. Although the cluster diameter was similar in both hemispheres, their spacing was about 20 percent Larger in the Left hemisphere. Assuming similar relations between functional and anatomical architecture as in visual cortex, the present data suggest that more functionally distinct columnar systems are included per surface unit in the Left than in the right area 22.