Sex differences in subcortical auditory processing emerge across development
Sex differences in subcortical auditory processing emerge across development
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DOI：
10.1016/j.heares.2019.07.002
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发表时间：
2019-09-01
期刊：
影响因子：
2.8
通讯作者：
Kraus, Nina
中科院分区：
文献类型：
--
作者：
Krizman, Jennifer;Bonacina, Silvia;Kraus, Nina
人类皮层下听觉处理是两性二态的。流行的观点——性别差异源于耳蜗的差异——仍未得到证实，这些差异在多大程度上反映了不同的听觉过程也是未知的。为了确定皮层下性别差异的起源，我们将516名参与者（250名女性）分为3-5岁、14-15岁和22-26岁三个年龄组，将其出现映射到听觉系统的外周到中枢成熟。为了研究这些性别差异是否来自不同的过程，我们比较了每个诱发反应成分的发展轨迹，并测试了它们预测参与者性别和年龄的能力。我们发现一些皮层下的性别差异在耳蜗成熟后很好地显现出来，并且每种测量方法都对预测参与者的人口统计数据有独特的贡献，这表明性别差异源于多个中枢听觉过程。(C) 2019年Elsevier B.V.出版
Human subcortical auditory processing is sexually dimorphic. The prevailing view - that sex differences arise from cochlear differences - remains unproven, and the extent to which these differences reflect distinct auditory processes is unknown. To determine the origin of subcortical sex differences, we mapped their emergence onto the peripheral-to-central maturation of the auditory system in 516 participants (250 female) across three age groups: 3-5, 14-15, and 22-26 years. To examine whether these sex differences arise from distinct processes, we compared developmental trajectories of each evoked-response component and tested their ability to predict a participant's sex and age. We find that some subcortical sex differences emerge well after the cochlea is mature and that each measure uniquely contributes to predicting participant demographics, indicating that sex differences arise from multiple central auditory processes. (C) 2019 Published by Elsevier B.V.