The Attentional Field Revealed by Single-Voxel Modeling of fMRI Time Courses
The Attentional Field Revealed by Single-Voxel Modeling of fMRI Time Courses
复制标题
DOI：
10.1523/jneurosci.3754-14.2015
复制
发表时间：
2015-03-25
影响因子：
5.3
通讯作者：
DeYoe, Edgar A.
中科院分区：
文献类型：
--
作者：
Puckett, Alexander M.;DeYoe, Edgar A.
视觉注意的空间地形学是视觉空间注意的许多理论模型的一个显著和关键特征。以前基于fMRI的注意力地形测量通常过于粗糙，无法充分测试不同竞争模型的预测。这项研究展示了一种新的技术，使详细测量地形的视觉空间注意力从单体素，功能磁共振成像的时间进程。简单地说，这种技术涉及首先估计体素的群体感受野（pRF），然后通过pRF“漂移”注意力，使得体素的fMRI时间过程的调制反映注意力的空间拓扑。的地形的注意力领域（AF），然后估计使用的时间过程建模过程。值得注意的是，我们能够在许多视觉区域进行这些测量，包括更小，更高阶的区域，从而能够在整个人类视觉皮层的整个层次中更全面地比较注意机制。使用这种技术，我们表明，AF规模与偏心率和不同的视觉区域。我们还表明，体素在多个视觉区域表现出抑制性的注意力的影响，以及具有增强高斯中心与抑制性的周围AF建模。这些发现提供了广泛的，定量的神经生理学数据用于模拟视觉空间注意的心理影响。
The spatial topography of visual attention is a distinguishing and critical feature of many theoretical models of visuospatial attention. Previous fMRI-based measurements of the topography of attention have typically been too crude to adequately test the predictions of different competing models. This study demonstrates a new technique to make detailed measurements of the topography of visuospatial attention from single-voxel, fMRI time courses. Briefly, this technique involves first estimating a voxel's population receptive field (pRF) and then "drifting" attention through the pRF such that the modulation of the voxel's fMRI time course reflects the spatial topography of attention. The topography of the attentional field (AF) is then estimated using a time-course modeling procedure. Notably, we are able to make these measurements in many visual areas including smaller, higher order areas, thus enabling a more comprehensive comparison of attentional mechanisms throughout the full hierarchy of human visual cortex. Using this technique, we show that the AF scales with eccentricity and varies across visual areas. We also show that voxels in multiple visual areas exhibit suppressive attentional effects that are well modeled by an AF having an enhancing Gaussian center with a suppressive surround. These findings provide extensive, quantitative neurophysiological data for use in modeling the psychological effects of visuospatial attention.