Environmental stress, psychological stress and allostatic load.
Environmental stress, psychological stress and allostatic load.
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DOI：
10.1080/13548500500429338
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发表时间：
2007-01-01
期刊：
影响因子：
--
通讯作者：
Hecker, Jane R
中科院分区：
文献类型：
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作者：
Clark, Michael S;Bond, Malcolm J;Hecker, Jane R
慢性压力导致健康状况不佳的机制还不清楚。目的是确定这种机制是否可能是非稳态负荷，这是一个新的概念，指定生理系统，可能会遭受累积磨损和撕裂后，慢性压力，共同导致健康状况不佳。该研究探讨了非稳态负荷与环境和心理压力在痴呆症的康复和放弃护理的背景下，是一个为期2年的纵向比较三组：80个新的痴呆症配偶照顾者，120个退伍军人照顾者，和60个非照顾者。数据包括非稳态负荷标记物和环境和心理应激措施。交叉滞后分析产生了心理压力和一个非稳态负荷成分（主要介质）之间的统计学显着关联。心理应激是一个更好的预测主要介质比环境应激。初级介质上升，随着时间的照顾者，但不为非照顾者。在第二年放弃其角色的照顾者的人数明显增加，尽管心理压力水平实际上有所下降。初级介质是非稳态负荷和先前应激之间关系的关键组成部分。当非稳态负荷被视为压力的结果时，区分环境压力和心理压力是很重要的。
The mechanism by which chronic caregiving stress results in poor health is not well understood. The objective was to determine whether such a mechanism may be allostatic load, a novel concept specifying physiological systems that may suffer cumulative wear and tear following chronic stress, leading collectively to poor health. The study examines the association of allostatic load with environmental and psychological stress in the contexts of dementia caregiving and relinquishment of care, and is a 2-year longitudinal comparison of three groups: 80 new dementia spouse caregivers, 120 veteran caregivers, and 60 non-caregivers. Data comprised allostatic load markers and environmental and psychological stress measures. Cross-lagged analyses produced a statistically significant association between psychological stress and one allostatic load component (primary mediators). Psychological stress was a better predictor of primary mediators than environmental stress. Primary mediators rose with time for caregivers, but not for non-caregivers. A greater rise was evident for caregivers who had relinquished their role by the second year, although the level of psychological stress actually declined. Primary mediators are a key component of the relationship between allostatic load and prior stress. When allostatic load is treated as an outcome of stress, it is important to distinguish environmental and psychological stress.