Pharmacovigilance of Alternative Medications in the Cancer Setting.

Pharmacovigilance of Alternative Medications in the Cancer Setting.
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癌症环境中替代药物的药物警戒。

DOI:
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发表时间:
2018
影响因子:
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通讯作者:
J. McKoy
J. McKoy
中科院分区:
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文献类型:
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作者:
D. Liebling;Emmanuel Cordova;G. Deng;J. McKoy

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随着越来越多地使用替代药物来管理癌症治疗相关的副作用,替代药物疗法(特别是草药补充剂)的药物警戒在肿瘤环境中变得越来越重要。本章的重点是药物警戒的草药补充剂在癌症药物治疗的设置,并探讨国家和国际药物政策,已被用来减轻不良草药补充剂事件(AHE)。本章探讨了常见的药物-草药补充剂相互作用,讨论了这些相互作用背后的机制,并调查了临床医生可以用来报告不良事件的几种常见药物警戒报告方法。本章还将描述可用于监测这些替代药物治疗使用的政策和策略,并检查全球协调努力,以减少癌症环境中的AHE。草药的安全性已成为国际公共卫生优先事项,我们探讨了肿瘤学提供者如何直接应用本文获得的知识,以帮助指导他们对使用替代药物的肿瘤患者的临床管理。
With the increase in utilization of alternative medications to manage cancer treatment-related side effects, pharmacovigilance of alternative drug therapies, specifically herbal supplements, has become of increasing importance in the oncologic setting. This chapter focuses on the pharmacovigilance of herbal supplements in the setting of cancer drug therapy and explores national and international drug policies that have been employed to mitigate adverse herbal supplement events (AHEs). This chapter examines common drug-herbal supplement interactions, discusses the mechanisms behind these interactions, and investigates several common pharmacovigilance reporting methods clinicians can use to report adverse events. This chapter will also describe policies and strategies that can be employed to monitor use of these alternative drug therapies, and examines global harmonization efforts to reduce AHEs in the cancer setting. The safety of herbal medicines has emerged as an international public health priority, and we explore how oncology providers may directly apply the knowledge garnered herein to help guide their clinical management of oncology patients utilizing alternative medications.
DOI: 10.1200/jco.2000.18.13.2505
发表时间: 2000-07-01
影响因子: 45.3
作者:
Richardson, MA;Sanders, T;Singletary, SE
通讯作者: Singletary, SE