Thyrotropin-releasing hormone in lamprey central nervous system.

Thyrotropin-releasing hormone in lamprey central nervous system.
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七鳃鳗中枢神经系统中的促甲状腺素释放激素。

DOI:
10.1016/0006-8993(85)90264-1
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发表时间:
1985
期刊:
影响因子:
2.9
通讯作者:
Selzer,ME
Selzer,ME
中科院分区:
医学3区
文献类型:
--
作者:
Youngs,LJ;Winokur,A;Selzer,ME

文献摘要

被引文献

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用放射免疫法测定了海鳗幼体、成体和成体中枢神经系统促甲状腺激素释放激素(TRH)的水平。在海鳗幼体中,脑下垂体复合体含有大约。脑组织TRH 609pg/mg,平均43.5±5.5pg/mg。脊髓含量为11.2±2.3pg/mg。成年海鳗和河鳗的相应水平相似。完整的脊柱横断并未显著改变病变下方的TRH水平。因此,脊髓含有TRH,独立于脊髓上轴突投射。
Thyrotropin-releasing hormone (TRH) levels were measured by radioimmunoassay in the CNS of larval and adult sea lampreys and adult river lampreys. In larval sea lampreys, the pituitary complex contained approx. 609 pg TRH/mg, brain contained 43.5 ± 5.5 pg/mg (mean ± S.E.M.). while the spinal cord contained 11.2 ± 2.3 pg/mg. Corresponding levels in the adult sea and river lampreys were similar. Complete spinal transection did not significantly alter TRH levels below the lesion. Thus, the spinal cord contains TRH independent of supraspinal axonal projections.