Analysis and interpretation of twin studies including measures of the shared environment
Analysis and interpretation of twin studies including measures of the shared environment
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DOI：
10.1111/j.1467-8624.2005.00845.x-i1
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发表时间：
2005-11-01
影响因子：
4.6
通讯作者：
Eaves, LJ
中科院分区：
文献类型：
--
作者：
Turkheimer, E;D'Onofrio, BM;Eaves, LJ
最近的报告使用经典的行为遗传学研究设计，其中双胞胎数据与他们共同的家庭环境的测量特征相结合，提出了惊人的主张，估计环境对行为的影响与遗传效应的控制。这些索赔被夸大有两个相关的原因。首先，当一个变量在家庭水平上被测量时，它必然等同于一起抚养的双胞胎，不可能将其划分为遗传和环境成分。其次，虽然结构方程模型和DeFries-Fulker分析是分析许多类型的双胞胎数据的可靠工具，但在估计测量的家庭水平变量的影响时，它们不能控制遗传或环境的混淆。
Recent reports using a classical behavior genetic research design in which twin data are combined with a measured characteristic of their shared family environment have made striking claims about estimating environmental influences on behavior with genetic effects controlled. Such claims are overstated for two related reasons. First, when a variable is measured at the family level in a way that makes it necessarily equivalent for twins reared together, it is not possible to partition it into genetic and environmental components. Second, although structural equation modeling and DeFries-Fulker analysis are sound tools for the analysis of many types of twin data, they do not control for genetic or environmental confounds when estimating the effect of measured family-level variables.