The prognostic significance of micrometastases in breast cancer: A SEER population-based analysis

The prognostic significance of micrometastases in breast cancer: A SEER population-based analysis
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DOI:
10.1245/s10434-007-9513-6
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发表时间:
2007-12-01
影响因子:
3.7
通讯作者:
Giuliano, Armando E.
Giuliano, Armando E.
中科院分区:
医学2区
文献类型:
--
作者:
Chen, Steven L.;Hoehne, Francesca M.;Giuliano, Armando E.

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引言:乳腺癌淋巴结微转移的预后意义存在争议。我们假设只有微转移的患者(N1 mi)的生存率介于有1-3个肿瘤阳性淋巴结的患者(N1)和无阳性淋巴结的患者(N 0)之间。方法:我们查询了1992年至2003年所有无远处转移的浸润性导管或小叶乳腺癌患者的监测、流行病学和最终结果(SEER)数据库,
Introduction: The prognostic significance of lymph node micrometastases in breast cancer is controversial. We hypothesized that the survival of patients with solely micrometastatic disease (N1mi) would be intermediate to patients with 1-3 tumor-positive lymph nodes (N1) and those with no positive lymph nodes (N0).Methods: We queried the surveillance, epidemiology and end results (SEER) database for all patients between 1992 and 2003 with invasive ductal or lobular breast cancer without distant metastases and