Anti-NMDA receptor encephalitis presenting with focal non-convulsive status epilepticus in a child.
Anti-NMDA receptor encephalitis presenting with focal non-convulsive status epilepticus in a child.
复制标题
儿童抗 NMDA 受体脑炎，表现为局灶性非惊厥性癫痫持续状态。
DOI：
10.1055/s-0031-1295408
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发表时间：
2011
期刊：
影响因子：
1.4
通讯作者：
Abend,NS
中科院分区：
文献类型：
--
作者：
Goldberg,EM;Taub,KS;Kessler,SK;Abend,NS
一名先前健康的9岁女孩因头痛、头晕、视力模糊和视觉异常而到急诊科就诊。她被诊断为偏头痛，进行了对症治疗，然后出院。几天后，她逐渐昏昏欲睡，并回到急诊室，在那里她被发现患有右下象限视和第六神经麻痹。脑部磁共振成像(MRI)显示左侧顶枕叶有脑回肿胀。连续脑电监测显示左侧枕区出现局灶性非惊厥性癫痫持续状态。脑脊液(CSF)抗NMDAR抗体阳性。本病例为首次报道的以局灶性非惊厥持续状态癫痫(NCSE)为表现的抗NMDAR脑炎。
A previously healthy 9-year-old girl presented to an emergency department (ED) with headache, dizziness, blurry vision, and abnormal visual perceptions. She was diagnosed with migraine, treated symptomatically, and discharged. Over the course of days, she became progressively somnolent, and returned to the ED, where she was found to have a right inferior quadrantanopsia and sixth nerve palsy. Magnetic resonance imaging (MRI) of the brain showed gyral swelling of the left parieto-occipital lobe. Continuous electroencephalogram (EEG) monitoring revealed focal non-convulsive status epilepticus (NCSE) in the left occipital region. Cerebrospinal fluid (CSF) was positive for antibodies directed against theN-methyl-d-aspartate receptor (NMDAR). This case is the first report of anti-NMDAR encephalitis presenting with focal non-convulsive status epilepticus (NCSE).