Monozygotic twins and triplets in association with blastocyst transfer
Monozygotic twins and triplets in association with blastocyst transfer
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DOI：
10.1023/b:jarg.0000029493.54929.be
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发表时间：
2004-04-01
影响因子：
3.1
通讯作者：
Paulson, RJ
中科院分区：
文献类型：
--
作者：
Jain, JK;Boostanfar, R;Paulson, RJ
目的：比较胚泡移植与第3天胚胎移植（ET）后单卵双胞胎的发生率。方法：回顾性分析1999-2000年期间使用胚泡ET的辅助生殖技术（ART）周期的结局，并与1997- 1998年期间接受第3天ET的类似患者组进行比较。结果：囊胚ET用于75个周期，移植2.0+/-2个胚胎。对照组包括90个周期，第3天ET和3.0+/-2胚胎transfered.Conclusions：高妊娠率保持与囊胚ET，即使较少的胚胎移植。囊胚期胚胎移植的单卵双胎率高于胚胎移植3天的单卵双胎率。这种增加可能部分抵消了减少高阶多胎妊娠归因于胚泡ET的好处。
Purpose: To compare the incidence of monozygotic twins following blastocyst versus day-3 embryo transfer (ET).Methods: A retrospective analysis of the outcome of assisted reproductive technology (ART) cycles utilizing blastocyst ET during 1999-2000 was compared to a similar group of patients undergoing day-3 ET during 1997-1998.Results: Blastocyst ET was used in 75 cycles with 2.0+/-2 embryos transferred. The comparison group consisted of 90 cycles with day-3 ET and 3.0+/-2 embryos transferred.Conclusions: High pregnancy rates are maintained with blastocyst ET even though fewer embryos are transferred. The rate of monozygotic twins is higher with blastocyst ET than with day-3 ET. This increase may partially negate the benefit of reduced high-order multiple gestations attributed to blastocyst ET.