Anxiety mediates the relationship between interpretation bias and paranoia in patients with persistent persecutory beliefs.
Anxiety mediates the relationship between interpretation bias and paranoia in patients with persistent persecutory beliefs.
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焦虑介导了有持续迫害信念的患者的解释偏差和偏执之间的关系。
DOI：
10.1080/10615806.2020.1802435
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Lam CLM
中科院分区：
文献类型：
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作者：
Lam CLM
背景和目的：解释偏差在产生和维持迫害信念/偏执方面的作用正逐渐在文献中确立，但负面情绪如何影响这种关系仍不清楚。本研究探讨焦虑和抑郁在持续性偏执狂患者解释偏执与偏执之间的中介作用。方法/设计：将中介模型应用于持续性偏执狂患者(N= 62)的临床资料，比较抑郁和焦虑程度对解释偏执与偏执之间关系的影响。结果：解释偏差和焦虑可以解释解释偏执的43%，解释解释偏差和抑郁的31%。焦虑水平，而不是抑郁水平，在一定程度上中介了解释偏见和偏执信念之间的关系。我们的数据表明，解释偏差和偏执信念之间的联系部分是通过焦虑水平的增加来实现的，尽管不是完全的。结论：本研究强调了焦虑在痛苦的偏执患者的解释偏差和偏执信念之间的联系中的中介作用。这些发现揭示了病理性偏执狂认知干预的潜在机制。试验登记：当前对照试验ISRCTN：90749868。注册日期追溯至2016年5月12日。
Background and Objectives:The role of interpretation bias in generating and maintaining persecutory beliefs/paranoid ideation is becoming established in the literature, but how negative mood affects this relationship remains unclear. The current study investigated the mediating role of anxiety and depression in the association between interpretation bias and paranoia in patients with persistent paranoia.Methods/Design:We applied the mediation model to clinical data gathered from patients with persistent paranoia (N= 62), and compared how levels of depression and anxiety affected the association between interpretation bias and paranoia.Results:Interpretation bias and anxiety accounted for 43% of the variance in paranoia, while interpretation bias and depression explained 31% of this variance. Levels of anxiety, but not depression, partially mediated the relationship between interpretation bias and paranoid beliefs. Our data suggest that the association between interpretation bias and paranoid beliefs takes effect partly, although not completely, through heightened levels of anxiety.Conclusions:The current study highlighted the role of anxiety as a mediator in the association between interpretation bias and paranoid beliefs in patients with distressing paranoia. These findings inform the potential mechanism underlying cognitive interventions for pathological paranoia.Trial registration:Current Controlled Trials ISRCTN: 90749868. Retrospectively registered on 12 May 2016.