Ruthenium-Catalyzed Decarboxylative C-H Alkenylation in Aqueous Media: Synthesis of Tetrahydropyridoindoles
Ruthenium-Catalyzed Decarboxylative C-H Alkenylation in Aqueous Media: Synthesis of Tetrahydropyridoindoles
复制标题
水介质中钌催化的脱羧 C-H 烯基化：四氢吡啶并吲哚的合成
DOI：
10.1021/acs.joc.8b00229
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发表时间：
2018-07-20
影响因子：
3.6
通讯作者：
Liu, Li
中科院分区：
文献类型：
--
作者：
Jin, Xiao-Yang;Xie, Li-Jun;Liu, Li
本文公开了在水溶液中具有宽底物范围的N-取代吲哚基羧酸的Ru（II）催化的脱羧和氧化偶联。该方法为在温和条件下合成各种吲哚稠环己基乙酸提供了一条可持续、高效的途径。
We disclose herein a Ru(II)-catalyzed decarboxylative and oxidative coupling of N-substituted indolyl carboxylic acids with broad substrate scope in an aqueous solution. This method provides a sustainable and efficient access to synthesize various indole-fused cyclohexanyl acetic acids under mild conditions.