Evidence of inhibitory interactions between neurons in dorsal cochlear nucleus.
Evidence of inhibitory interactions between neurons in dorsal cochlear nucleus.
复制标题
耳蜗背核神经元之间抑制相互作用的证据。
DOI：
10.1152/jn.1980.44.1.76
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发表时间：
1980
影响因子：
2.5
通讯作者：
Young,ED
中科院分区：
文献类型：
--
作者：
Voigt,HF;Young,ED
3.在II/III型-IV型对抑制槽，II/III型单位的反应地图的兴奋区主要是在IV型单位的反应地图的抑制区域内，在这一组的兴奋区的最大重叠为6分贝。另一方面，四对中，没有观察到抑制谷有更大的重叠兴奋区。在12对抑制谷中的11对中，II/III型单位几乎没有或没有自发活动（小于2.5峰/秒）。4.在一种情况下，IV型细胞的反应地图之前和之后，由于同时记录的II/III型神经元损伤的消失观察。IV型反应图的抑制区最初与II/III型细胞兴奋区重叠的部分在II/III型单位丢失后部分转化为兴奋区。5.交叉相关图，获得了20对组成的两个IV型单位。在一半的情况下，交叉相关图中没有显著的特征。在七种情况下，交叉相关图在原点附近有一对兴奋峰，这很可能是由于共享输入的影响。其余3例病例具有复杂的交叉相关图。在所有IV型-IV型对中，两个单位的反应图广泛重叠。6.这些结果是一致的想法，即II/III型反应记录从中间神经元的DCN，有助于抑制终端的细胞与IV型反应特性。
3. In type II/III-type IV pairs with inhibitory troughs, the excitatory area of the type II/III unit’s response map was largely within the inhibitory region of the type IV unit’s response map; the maximum overlap of excitatory areas in this group was 6 dB. On the other hand, four of the five pairs in which no inhibitory trough was observed had greater overlap of excitatory areas. In 11 of the 12 pairs with an inhibitory trough, the type II/III unit had little or no spontaneous activity (less than 2.5 spikes/s). 4. In one case the response map of a type IV cell was observed before and after the disappearance due to injury of a simultaneously recorded type II/III neuron. The portion of the inhibitory region of the type IV’s response map originally overlapped by the type II/III cell’s excitatory area was partially transformed into an excitatory region following loss of the type II/III unit. 5. Cross-correlograms were obtained for 20 pairs consisting of two type IV units. In half the cases there were no significant features in the cross-correlograms. In seven cases the cross-correlograms had a pair of excitatory peaks in the vicinity of the origin, which are most likely due to the effects of shared input. The remaining three cases had complex cross-correlograms. The response maps of the two units in all type IV-type IV pairs overlapped extensively. 6. These results are consistent with the idea that the type II/III responses are recorded from interneurons in the DCN that contribute inhibitory terminals to cells with type IV response properties.