Memory for remote events in chronic alcoholics and alcoholic Korsakoff patients.

Memory for remote events in chronic alcoholics and alcoholic Korsakoff patients.
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慢性酗酒者和酒精科尔萨科夫患者对遥远事件的记忆。

DOI:
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发表时间:
1980
影响因子:
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通讯作者:
J. Levin
J. Levin
中科院分区:
医学4区
文献类型:
--
作者:
M. Albert;N. Butters;J. Levin

文献摘要

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在1971年,Ryback假设了一系列与酒精滥用有关的认知障碍,包括重度社交饮酒者,长期酗酒者和患有Korsakoff综合征的酗酒者。自本文发表以来,一些调查表明,酒精性科尔萨科夫患者的一些认知和记忆缺陷特征在脱毒的慢性酒精中毒者中也很明显。与Korsakoff患者一样,慢性酗酒者在数字符号替换任务中也会受到损害(Glosser、Butters和Kaplan,1977年; Kapur和Butters,1977年; Butters、Cermak、Adinolfi和蒙哥马利,1977年)、识别嵌入图形(Glosser等人,1977; Kapur and Butters,1977),以及概念形成任务(Tarter and Parsons,1971; Oscar-Berman,1973)。在本书的前一章中,瑞安、巴特斯和他们的同事已经证明,戒毒后的酗酒者会出现短期记忆和学习问题,这与科萨科夫患者的情况相似。然而,所有这些比较都缺少对患者逆行性遗忘症的评估。众所周知,酗酒的科萨科夫人很难回忆起发病前的事情,但这种远程记忆丧失的潜在过程及其在非科萨科夫酗酒者中的流行程度尚不清楚。
In 1971, Ryback postulated a continuum of cognitive impainient related to alcohol abuse that encompassed heavy social drinkers, long-term alcoholics, and alcoholics with Korsakoff’s syndrome. Since the publication of this paper, several investigations have demonstrated that some of the cognitive and memory deficits characteristic of alcoholic Korsakoff patients are also apparent in detoxified chronic alcoholics. Like Korsakoff patients, chronic alcoholics are impaired on digit-symbol substitution tasks (Glosser, Butters and Kaplan, 1977; Kapur and Butters, 1977; Butters, Cermak, Adinolfi and Montgomery, 1977), the identification of embedded figures (Glosser et al., 1977; Kapur and Butters, 1977), and on concept formation tasks (Tarter and Parsons, 1971; Oscar-Berman, 1973). In the previous chapter of this book, Ryan, Butters and their associates have shown that detoxified alcoholics have short-term memory and learning problems that parallel those of the Korsakoff patients. Missing from all of these comparisons, however, has been the assessment of the patients’ retrograde amnesia. It is well known that alcoholic Korsakoffs have great difficulty recalling events prior to the onset of their illness, but the processes underlying this loss of remote memories and its prevalence among non-Korsakoff alcoholics are unknown.