The low affinity IgE Fc receptor (CD23) participates in B cell activation.
The low affinity IgE Fc receptor (CD23) participates in B cell activation.
复制标题
低亲和力 IgE Fc 受体 (CD23) 参与 B 细胞激活。
DOI：
10.1007/978-1-4615-3396-2_19
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发表时间：
1992
影响因子：
--
通讯作者：
Tygrett,LT
中科院分区：
文献类型：
--
作者：
Waldschmidt,TJ;Tygrett,LT
The low affinity IgE Fc receptor (FcɛRII or CD23) is expressed on all mature B lymphocytes (reviewed in 1 and 2). The FcʵRII is a 45 to 49 KD glycoprotein, and is categorized as a class II transmembrane molecule on account of its inverted membrane orientation. In addition to the transmembrane form of the receptor, a soluble form is readily released from B cells, a result of cleavage by a cell surface protease. cDNA cloning has revealed that the FceRII is a member of the hepatic lectin family, a somewhat unusual finding since all other characterized Fc receptors are known to be members of the immunoglobulin (Ig) gene superfamily.
