fNIRS Studies on Hemispheric Asymmetry in Atypical Neural Function in Developmental Disorders.
fNIRS Studies on Hemispheric Asymmetry in Atypical Neural Function in Developmental Disorders.
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DOI：
10.3389/fnhum.2017.00137
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发表时间：
2017
影响因子：
2.9
通讯作者：
Shinohara K
中科院分区：
文献类型：
--
作者：
Doi H;Shinohara K
功能偏侧化是人类神经系统具有高度可复制性的特征。许多先前的研究表明，注意力缺陷/多动障碍（ADHD）和自闭症谱系障碍（ASD）的人在非典型神经功能中表现出半球不对称的可能性。然而，尽管相关研究丰富，但对这一问题仍存在争议。在目前的小型审查，我们提供了一个概述的半球不对称的非典型神经功能的fNIRS研究中观察到的人与这些条件。非典型神经功能被定义为任务相关的氧合血红蛋白浓度变化的组间差异。现有的fNIRS研究支持ADHD儿童的右偏侧化大脑皮层。同时，我们没有发现ASD患者的非典型激活存在明显的左偏侧化。在此基础上，讨论了现有研究的现状和局限性。
Functional lateralization is highly replicable trait of human neural system. Many previous studies have indicated the possibility that people with attention-deficits/hyperactivity-disorder (ADHD) and autism spectrum disorder (ASD) show hemispheric asymmetry in atypical neural function. However, despite the abundance of relevant studies, there is still ongoing controversy over this issue. In the present mini-review, we provide an overview of the hemispheric asymmetry in atypical neural function observed in fNIRS studies on people with these conditions. Atypical neural function is defined as group-difference in the task-related concentration change of oxygenated hemoglobin. The existing fNIRS studies give support to the right-lateralized atypicalty in children with ADHD. At the same time, we did not find clear leftward-lateralization in atypical activation in people with ASD. On the basis of these, we discuss the current states and limitation of the existing studies.