Psychological distress, emotional stability, and emotion regulation moderate dynamics of herpes simplex virus type 2 recurrence.
Psychological distress, emotional stability, and emotion regulation moderate dynamics of herpes simplex virus type 2 recurrence.
复制标题
心理困扰、情绪稳定性和情绪调节调节 2 型单纯疱疹病毒复发的动态。
DOI：
10.1007/s12160-014-9640-9
复制
发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Strachan,Eric
中科院分区：
文献类型：
--
作者：
Horn,ErinE;Turkheimer,Eric;Strachan,Eric
BackgroundHerpes simplex virus type 2（HSV-2）生殖器病变复发是由心理因素调节的，但在human.PurposeThe平均心理痛苦、情绪稳定和情绪调节对HSV-2复发的调节作用进行了测试，结果显示，HSV-2血清阳性的19名妇女随访22周以上。收集HSV-2复发和心理困扰的每日测量值。HSV-2病变和病毒脱落被建模为线性振荡器系统，与心理困扰缓和的周期性的每个processing.ResultsHigh水平的困扰，更不稳定的情绪，和更少的能力来调节情绪状态与病变发作之间的天数较少。病毒脱落表现出相同的pattern.ConclusionsResults是一致的研究表明，心理困扰抑制免疫系统功能，并提供新的证据表明，生殖器HSV-2病毒脱落相关，并调节，心理困扰。
BackgroundHerpes simplex virus type 2 (HSV-2) genital lesion recurrence is modulated by psychological factors, but no such link with viral shedding (and thus asymptomatic transmission) has been observed in humans.PurposeThe moderating effects of average psychological distress, emotional stability, and emotion regulation on HSV-2 recurrence were tested.MethodsNineteen HSV-2 seropositive women were followed over 22 weeks. Daily measures of HSV-2 recurrence and psychological distress were collected. HSV-2 lesions and viral shedding were modeled as linear oscillator systems, with psychological distress moderating the periodicity of each process.ResultsHigh levels of distress, more labile moods, and less ability to regulate emotional states were associated with fewer days elapsed between the onset of lesion episodes. Viral shedding showed the same pattern.ConclusionsResults are consistent with research indicating that psychological distress suppresses immune system functioning, and provide new evidence that genital HSV-2 viral shedding is related to, and regulated by, psychological distress.