Obesity and dyslipidemia
Obesity and dyslipidemia
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DOI：
10.1016/s0889-8529(03)00073-2
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发表时间：
2003-12-01
影响因子：
4.5
通讯作者：
Robbins, DC
中科院分区：
文献类型：
--
作者：
Howard, BV;Ruotolo, G;Robbins, DC
与肥胖相关的血脂异常的特征是甘油三酯升高，高密度脂蛋白降低，低密度脂蛋白组成异常。此外，肥胖相关的血脂异常在肥胖者动脉粥样硬化和心血管疾病(CVD)的发展中起着重要作用。减肥和锻炼，即使它们不能使体重正常化，也可以改善这种血脂异常，从而降低心血管疾病的风险。此外，必要时应针对肥胖者进行强化降脂治疗。
Dyslipidemia related to obesity is characterized by increased triglycerides, decreased high-density lipoproteins, and abnormal low density lipoprotein composition. In addition, the dyslipidemia associated with obesity plays a major role in the development of atherosclerosis and cardiovascular disease (CVD) in obese individuals. Weight loss and exercise, even if they do not result in normalization of body weight, can improve this dyslipidemia and thus reduce CVD risk. In addition, obese individuals should be targeted for intense lipid-lowering therapy, when necessary.