Urban aerosols harbor diverse and dynamic bacterial populations
Urban aerosols harbor diverse and dynamic bacterial populations
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DOI：
10.1073/pnas.0608255104
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发表时间：
2007-01-02
影响因子：
11.1
通讯作者：
Andersen, Gary L.
中科院分区：
文献类型：
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作者：
Brodie, Eoin L.;DeSantis, Todd Z.;Andersen, Gary L.
考虑到其对人类健康、农业生产力以及生态系统稳定性的潜在影响的重要性，令人惊讶的是，对于大气中微生物居民的组成或动态，我们知之甚少。我们使用一种定制的高密度DNA微阵列，在17周的时间里对美国两个城市的细菌种群进行了检测和监测。这些城市气溶胶中至少包含1800种不同的细菌类型，其丰富度接近某些土壤细菌群落。我们还揭示了包含致病成员的细菌家族的持续存在，其中包括具有生物恐怖主义重要意义的特定病原体的环境亲缘物种。最后，通过多元回归技术，我们证明了在塑造我们所呼吸空气的生物组成方面，时间和气象的影响可能是比地理位置更强的因素。
Considering the importance of its potential implications for human health, agricultural productivity, and ecosystem stability, surprisingly little is known regarding the composition or dynamics of the atmosphere's microbial inhabitants. Using a custom high-density DNA microarray, we detected and monitored bacterial populations in two U.S. cities over 17 weeks. These urban aerosols contained at least 1,800 diverse bacterial types, a richness approaching that of some soil bacterial communities. We also reveal the consistent presence of bacterial families with pathogenic members including environmental relatives of select agents of bioterrorism significance. Finally, using multivariate regression techniques, we demonstrate that temporal and meteorological influences can be stronger factors than location in shaping the biological composition of the air we breathe.