A winged helix protein from yeast Saccharomyces cerevisiae recognizes centromere sequences.
A winged helix protein from yeast Saccharomyces cerevisiae recognizes centromere sequences.
复制标题
来自酿酒酵母的翼状螺旋蛋白可识别着丝粒序列。
DOI：
10.1006/abbi.1999.1638
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发表时间：
2000
期刊：
影响因子：
--
通讯作者：
Liao,X
中科院分区：
文献类型：
--
作者：
Myrich,E;Shiyanova,T;Liao,X
The winged helix–turn–helix motif was initially identified in the mammalian hepatocyte-enriched transcription factor HNF-3 and the Drosophila forkhead homeotic protein. Proteins containing the winged helix motif have been shown to play important roles in tissue-specific developmental regulation. In this report, by using a genomic binding site selection method, we demonstrate that the winged helix protein YFKH-1 from the yeast Saccharomyces cerevisiae recognizes conserved sequence in yeast centromeres. Thus, our data suggest that the winged helix proteins of the yeast may be involved in centromeric functions of the yeast.
