Setting priorities for global mental health research
Setting priorities for global mental health research
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DOI：
10.2471/blt.08.054353
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发表时间：
2009-06-01
期刊：
影响因子：
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通讯作者：
Patel, Vikram
中科院分区：
文献类型：
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作者：
Tomlinson, Mark;Rudan, Igor;Patel, Vikram
目的 确定全球心理健康研究的投资重点，并提出在这个资源不足和调查不足的领域更合理地使用资金。 方法 《柳叶刀》心理健康小组的成员系统地列出了四大类疾病的研究投资方案并对其进行评分：精神分裂症和其他主要精神障碍、重度抑郁症和其他常见精神障碍、酗酒和其他药物滥用障碍以及广泛的儿童和精神障碍。 青春期精神障碍。该小组利用儿童健康和营养研究计划的优先顺序设定方法，列出了各种研究问题，并使用可回答性、有效性、可交付性、公平性以及对精神健康障碍持续负担的潜在影响等标准对其进行了评估。然后根据更多利益相关者群体表达的价值观体系对分数进行加权。调查结果得分最高的研究问题与卫生政策和系统研究有关，在资源匮乏的情况下在何处以及如何提供现有的具有成本效益的干预措施，以及对儿童和青少年精神障碍的广泛类别或与酒精和药物滥用问题有关的流行病学研究。得分最低的问题与新干预措施和新药物或药理学制剂、疫苗或其他技术的开发有关。 结论 在全球心理健康的背景下，在未来 10 年的时间框架内，最好通过投资于卫生政策和系统、流行病学的研究以及改进具有成本效益的干预措施的实施来填补关键知识空白。
Objective To set investment priorities in global mental health research and to propose a more rational use of funds in this under-resourced and under-investigated area.Methods Members of the Lancet Mental Health Group systematically listed and scored research investment options on four broad classes of disorders: schizophrenia and other major psychotic disorders, major depressive disorder and other common mental disorders, alcohol abuse and other substance abuse disorders, and the broad class of child and adolescent mental disorders. Using the priority-setting approach of the Child Health and Nutrition Research Initiative, the group listed various research questions and evaluated them using the criteria of answerability, effectiveness, deliverability, equity and potential impact on persisting burden of mental health disorders. Scores were then weighted according to the system of values expressed by a larger group of stakeholders.Findings The research questions that scored highest were related to health policy and systems research, where and how to deliver existing cost-effective interventions in a low-resource context, and epidemiological research on the broad categories of child and adolescent mental disorders or those pertaining to alcohol and drug abuse questions. The questions that scored lowest related to the development of new interventions and new drugs or pharmacological agents, vaccines or other technologies.Conclusion In the context of global mental health and with a time frame of the next 10 years, it would be best to fill critical knowledge gaps by investing in research into health policy and systems, epidemiology and improved delivery of cost-effective interventions.