Making memories: Brain activity that predicts how well visual experience will be remembered

Making memories: Brain activity that predicts how well visual experience will be remembered
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DOI:
10.1126/science.281.5380.1185
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发表时间:
1998-08-21
期刊:
影响因子:
56.9
通讯作者:
Gabrieli, JDE
Gabrieli, JDE
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Brewer, JB;Zhao, Z;Gabrieli, JDE

文献摘要

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经历会被记住或遗忘,但是记忆命运的神经决定因素是未知的。事件相关的功能性磁共振成像被用来识别区分视觉体验的特定大脑激活,这些视觉体验后来被记住了,记忆不太好,或者被遗忘了。在扫描内侧颞叶和额叶区域时,受试者观看复杂的彩色照片。研究对象随后接受了对照片的记忆测试。右前额叶皮层和双侧海马旁皮层的局灶性激活的大小预测了哪些照片后来被记住了,哪些记忆不太好,或者被遗忘了。
Experiences are remembered or forgotten, but the neural determinants for the mnemonic fate of experience are unknown. Event-related functional magnetic resonance imaging was used to identify specific brain activations that differentiated between visual experiences that were later remembered well, remembered less well, or forgotten. During scanning of medial temporal lobe and frontal lobe regions, subjects viewed complex, color photographs. Subjects later received a test of memory for the photographs. The magnitudes of focal activations in right prefrontal cortex and in bilateral parahippocampal cortex predicted which photographs were later remembered well, remembered less well, or forgotten.