The pathogenesis of acute allograft dysfunction in desensitized renal transplant recipients
The pathogenesis of acute allograft dysfunction in desensitized renal transplant recipients
复制标题
脱敏肾移植受者急性同种异体移植功能障碍的发病机制
DOI：
10.1111/j.1399-0012.2012.01684.x
复制
发表时间：
2012-07-01
影响因子：
2.1
通讯作者：
Pelletier, R. P.
中科院分区：
文献类型：
--
作者：
Singh, N.;Sun, Q.;Pelletier, R. P.
背景HLA脱敏后的急性同种异体移植排斥反应在移植后早期很常见，但导致移植物功能障碍的组织病理学变化顺序尚未明确。方法通过研究35例失敏活体供肾受者移植后早期活检的过程，评估抗体介导的移植物损伤的早期发病机制和顺序。
Background Acute allograft rejection after HLA desensitization is common early post-transplant but the sequence of histopathologic changes leading to graft dysfunction has not been well defined. Methods We evaluated the early pathogenesis and sequence of antibody-mediated graft damage of 35 desensitized living donor kidney recipients by studying the course of biopsies taken in the very early post-transplant period (