Molecular MRI of Atherosclerotic Plaque With Targeted Contrast Agents.
Molecular MRI of Atherosclerotic Plaque With Targeted Contrast Agents.
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DOI:
10.1007/s12410-009-0012-y
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发表时间:
2009-04-01
影响因子:
0.9
通讯作者:
Caravan, Peter
中科院分区:
文献类型:
--
作者:
Sosnovik, David E;Caravan, Peter
Molecular MRI of atherosclerosis involves the use of novel contrast agents to image cellular and molecular processes within atherosclerotic plaque. Agents to image plaque lipid content, inflammation, angiogenesis, and thrombosis have been developed and studied extensively in animal models of atherosclerosis and vascular injury. Selected agents have also been studied in humans, with highly promising initial results. In this brief review, recent advances as well as opportunities and challenges in the field are discussed.