Absent Contrast Filling of Ipsilateral Superficial Middle Cerebral Vein Predicts Midline Shift in Acute Middle Cerebral Artery Occlusion.
Absent Contrast Filling of Ipsilateral Superficial Middle Cerebral Vein Predicts Midline Shift in Acute Middle Cerebral Artery Occlusion.
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同侧大脑中浅静脉缺乏对比充盈预示着急性大脑中动脉闭塞的中线移位
DOI：
10.3389/fneur.2020.570844
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发表时间：
2020
影响因子：
3.4
通讯作者：
Geng Y
中科院分区：
文献类型：
--
作者：
Zhang S;Lin L;Zhang R;Wang M;Yu Y;Shi Z;Parsons M;Geng Y
背景与目的：中线移位是急性大动脉闭塞（LAO）的一种危及生命的并发症。浅脑中静脉（SMCV）预测急性LAO患者中线移位的价值目前尚不清楚。方法：纳入2018年3月至2019年5月连续急性LAO（大脑中动脉M1±颅内颈内动脉）患者。同侧皮质静脉无充盈（标记为SMCV -）定义为在缺血半球CT灌注的四维计算机断层扫描（CT）血管造影的整个静脉期均无造影剂充盈。结果：81例患者中，31例（38.4%）被鉴定为SMCV -。SMCV独立预测中线移位，敏感性为87.5%，特异性为82.5%。受试者工作特征分析显示，除基线缺血核心容积外，将SMCV -作为预测中线移位的预测指标，可显著增加曲线下面积（SMCV -与基线缺血核心容积相比：AUC = 0.903 vs. 0.841, Z = 2.451, P = 0.014）。结论：在急性LAO患者中，SMCV -的存在是中线移位的敏感和特异性影像学标志物。在预测中线移位方面，SMCV -对基线缺血核心容量有补充价值。
Background and purpose: Midline shift is a life-threatening complication of acute large artery occlusion (LAO). The value of superficial middle cerebral vein (SMCV) for predicting midline shift is currently unclear for patients with acute LAO. Methods: Consecutive acute LAO (middle cerebral artery M1 ± intracranial internal carotid artery) patients between March 2018 and May 2019 were included. Absent filling of ipsilateral cortical vein (marked as SMCV–) was defined as no contrast filling into the vein across the whole venous phase of four-dimensional computed tomography (CT) angiography derived from CT perfusion in the ischemic hemisphere. Results: In the total of 81 patients, 31 (38.4%) were identified as SMCV–. SMCV– independently predicted midline shift, with sensitivity of 87.5% and specificity of 82.5%. Receiver operating characteristic analysis showed that including SMCV– as a predictor in addition to baseline ischemic core volume significantly increased the area under the curve in predicting midline shift (SMCV– with baseline ischemic core volume vs. baseline ischemic core volume: AUC = 0.903 vs. 0.841, Z = 2.451, P = 0.014). Conclusion: In acute LAO patients, the presence of SMCV– was a sensitive and specific imaging marker for midline shift. SMCV– had supplementary value to baseline ischemic core volume in predicting midline shift.
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影响因子：
19.7
作者：
Bivard, Andrew;Levi, Christopher;Parsons, Mark
通讯作者：
Parsons, Mark
影响因子：
3.7
作者：
Jo K;Bajgur SS;Kim H;Choi HA;Huh PW;Lee K
通讯作者：
Lee K
同侧大脑浅静脉充盈不足与再灌注治疗后的不良结果相关
影响因子：
8.3
作者：
Zhang S;Lai Y;Ding X;Parsons M;Zhang JH;Lou M
通讯作者：
Lou M
影响因子：
48
作者：
Hofmeijer, Jeannette;Kappelle, L. Jaap;van der Worp, H. Bart
通讯作者：
van der Worp, H. Bart
影响因子：
3.5
作者：
Dargazanli, C.;Consoli, A.;Lapergue, B.
通讯作者：
Lapergue, B.