Is insight in mania state-dependent? A meta-analysis
Is insight in mania state-dependent? A meta-analysis
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DOI：
10.1097/01.nmd.0000145036.76435.c3
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发表时间：
2004-11-01
影响因子：
1.9
通讯作者：
Rosenquist, KJ
中科院分区：
文献类型：
--
作者：
Ghaemi, SN;Rosenquist, KJ
在第一个评估躁狂症自知力研究的荟萃分析中，我们试图确定躁狂症的自知力是状态依赖性的还是特质样的。在精神分裂症中，洞察力是一种类似特质的状态。如果是状态依赖性的，躁狂症的自知力将不同于精神分裂症的自知力，并且不同的治疗和研究意义将随之而来。通过MEDLINE文献检索，确定了7份使用标准化躁狂症自知力量表的报告。四项纵向研究被纳入荟萃分析。荟萃分析发现，洞察力似乎是状态依赖的。从急性躁狂恢复后，Insight显示改善20%（95%置信区间，7%至34%）（p = .003）。随着急性躁狂发作的消退，双相情感障碍患者的自知力得到改善，这表明双相情感障碍患者的自知力是状态依赖性的。我们认为，受损的洞察力被认为是急性躁狂症的诊断图片的一部分。
In the first meta-analysis of studies assessing insight in mania, we sought to determine whether insight in mania is state-dependent or a trait-like condition. In schizophrenia, insight is a trait-like condition. If state-dependent, insight in mania would differ from insight in schizophrenia, and different treatment and research implications would follow. Seven reports using standardized insight rating scales in mania were identified through a MEDLINE literature search. Four longitudinal studies were included in a meta-analysis. The meta-analysis found that insight appears to be state-dependent. Insight showed a 20% improvement (95% confidence intervals, 7% to 34%) after recovery from acute mania (p = .003). Insight improves in bipolar disorder with resolution of the acute manic episode, suggesting that insight is state-dependent in bipolar disorder. We suggest that impaired insight be considered as part of the diagnostic picture of acute mania.