Localized lesions of ventral striatum, but not arcopallium, enhanced impulsiveness in choices based on anticipated spatial proximity of food rewards in domestic chicks
Localized lesions of ventral striatum, but not arcopallium, enhanced impulsiveness in choices based on anticipated spatial proximity of food rewards in domestic chicks
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DOI：
10.1016/j.bbr.2005.10.002
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发表时间：
2006-03-15
影响因子：
2.7
通讯作者：
Matsushima, T
中科院分区：
文献类型：
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作者：
Aoki, N;Suzuki, R;Matsushima, T
在1-2周龄的家鸡中，研究了双侧腹侧纹状体（中脑纹状体的中脑核及其周围区域）和Arcopallium（鸟类端脑的主要下降区域）的化学损伤的影响。使用Y-迷宫，我们分析了损伤对受试鸡在两个具有相同经济后果的任务中所做选择的影响，即，小而近的食物奖励与大而远的食物奖励。在任务1中，红色、黄色和绿色珠子与放置在离小鸡不同距离处的喂食器相关联;小鸡因此通过珠子的颜色来预测食物的空间接近度，而食物的数量是固定的。在任务2中，喂食器上的红色和黄色旗帜与不同数量的食物相关联;小鸡因此通过旗帜的颜色来预测食物的数量，而奖励的接近程度可以直接通过视觉来确定。在任务1中，双侧腹侧纹状体（但不是arcopallium）的病变增强了小鸡的冲动性的选择，这表明选择的基础上预期的接近选择性地改变。在任务2中，腹侧纹状体的类似病变并没有改变选择。在这两个实验中，小鸡的运动功能保持不变，表明病变不影响觅食效率，即，食物的客观价值。腹侧纹状体（而不是arcopallium）的预期食物奖励的神经相关性可以让小鸡在接近遥远的食物资源时投入适量的工作成本。(c)2005 Elsevier B. V.保留所有权利。
The effects of bilateral chemical lesions of the ventral striatum (nucleus accumbens and the surrounding areas in the media] striatum) and arcopallium (major descending area of the avian telencephalon) were examined in 1-2-weeks old domestic chicks. Using a Y-maze, we analyzed the lesion effects on the choices that subject chicks made in two tasks with identical economical consequences, i.e., a small-and-close food reward vs. a large-and-distant food reward. In task 1, red, yellow, and green beads were associated with a feeder placed at various distances from the chicks; chicks thus anticipated the spatial proximity of food by the bead's color, whereas the quantity of the food was fixed. In task 2, red and yellow flags on the feeders were associated with various amount of food; the chicks thus anticipated the quantity of food by the flag's color, whereas the proximity of the reward could be directly visually determined. In task 1, bilateral lesions of the ventral striatum (but not the arcopallium) enhanced the impulsiveness of the chicks' choices, suggesting that choices based on the anticipated proximity were selectively changed. In task 2, similar lesions of the ventral striatum did not change choices. In both experiments, motor functions of the chicks remained unchanged, suggesting that the lesions did not affect the foraging efficiency, i.e., objective values of food. Neural correlates of anticipated food rewards in the ventral striatum (but not those in the arcopallium) could allow chicks to invest appropriate amount of work-cost in approaching distant food resources. (c) 2005 Elsevier B.V. All rights reserved.