Chlorine: State of the art
Chlorine: State of the art
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DOI：
10.1007/s00408-004-2530-3
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发表时间：
2005-05-01
期刊：
影响因子：
5
通讯作者：
Evans, RB
中科院分区：
文献类型：
--
作者：
Evans, RB
氯是一种广泛使用的工业化学品。个人可能通过运输事故、工业暴露或滥用家用清洁剂而接触氯。虽然大多数暴露个体恢复正常的肺功能，但氯可导致各种肺损伤，包括肺水肿、限制性肺病和阻塞性疾病，包括反应性气道功能障碍综合征。氯暴露的残留效应是暴露强度、暴露期间的每分钟通气量和宿主特征（如吸烟和特应性）的函数。这本专著将总结氯的使用，事故的可能性，氯中毒在肺中的机制，并审查氯暴露对肺的急性和慢性影响，以及大量氯暴露的全身效应。
Chlorine is a widely used industrial chemical. Individuals can be exposed to chlorine through transportation accidents, industrial exposures or misuse of domestic cleaners. While most exposed individuals recover normal pulmonary function, chlorine can cause a variety of lung injuries including pulmonary edema, restrictive lung disease, and obstructive disease, including Reactive Airways Dysfunction Syndrome. Residual effects of chlorine exposure are a function of intensity of exposure, minute ventilation during exposure, and host characteristics such as cigarette smoking and atopy. This monograph will summarize uses of chlorine, the potential for accidents, the mechanism of chlorine toxicity in the lung, and review acute and chronic effects of chlorine exposure on the lung, as well as systemic effects of massive chlorine exposure.