INFLUENCE OF ACUTE PSYCHIC STRESS SITUATIONS ON BIOCHEMICAL AND VEGETATIVE PARAMETERS OF ESSENTIAL HYPERTENSIVES AT EARLY STAGE OF DISEASE
INFLUENCE OF ACUTE PSYCHIC STRESS SITUATIONS ON BIOCHEMICAL AND VEGETATIVE PARAMETERS OF ESSENTIAL HYPERTENSIVES AT EARLY STAGE OF DISEASE
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DOI：
10.1159/000286484
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发表时间：
1973-01-01
影响因子：
22.8
通讯作者：
LAUTER, J
中科院分区：
文献类型：
--
作者：
BAUMANN, R;ZIPRIAN, H;LAUTER, J
在精神压力情况下（在时间压力下反复心算）对15至25岁的男性正常人和处于疾病早期阶段的高血压患者（相当于世卫组织分类的“轻度高血压”）进行检查。应激情况影响：两组脉搏率、收缩压、舒张压均升高；高血压患者脉搏率和血糖持续升高；耗氧量和肌肉张力增加（高血压患者的初始值和应激后的值均高于对照组）；血浆中去甲肾上腺素、游离脂肪酸、皮质醇和肾素活性升高（直立效应）。与对照组相比，高血压患者对重复实验应激情况的适应明显受到干扰。
Normal persons and hypertensives at the early stage of the disease (corresponding to ‘mild hypertension’ as classified by the WHO) of male sex between 15 and 25 years were examined during a psychic stress situation (repeated mental arithmetic under time-pressure). The stress situation effected: rise of the pulse rate, of systolic and diastolic blood pressure in both groups; a prolonged persistence of increased pulse rate and blood glucose in hypertensives; increased oxygen consumption and muscular tonus (both the initial values and the values after stress situations were higher in hypertensives than in the control group); rise of noradrenalin, free fatty acids, cortisol and renin activity (orthostasis effect) in the plasma. In contrast to the control group the adaptation of hypertensives to repeated experimental stress situations was markedly disturbed.