Thresholds for human perception of roll tilt motion: patterns of variability based on visual, vestibular, and mixed cues.
Thresholds for human perception of roll tilt motion: patterns of variability based on visual, vestibular, and mixed cues.
复制标题
DOI：
10.1097/mao.0000000000000346
复制
发表时间：
2014-06
期刊：
影响因子：
--
通讯作者：
Merfeld D
中科院分区：
文献类型：
--
作者：
Mardirossian V;Karmali F;Merfeld D
视觉和前庭线索提供了不同的空间方位信息。我们之前的一项研究表明，当大脑判断侧倾方向时，视觉和前庭线索会融合在一起。然而，尚不清楚在视觉前庭条件下测量的运动感知阈值是否优于高频下的视觉或前庭阈值。前庭评估的创新方法-前庭阈值的测量，被使用。这种敏感的测试可能代表一个有前途的临床工具，在评估和治疗前庭和其他平衡障碍。我们使用了一个带有专用软件的穆格移动的平台。在1、2、3、4和5 Hz下对4名受试者进行了自适应降低幅度的测试。要求受试者在3种条件下指示运动方向：仅前庭-受试者在黑暗中滚动倾斜，仅视觉-视觉场景在受试者面前倾斜，以及组合视觉-前庭-受试者在观看静止视觉场景时旋转。视觉和前庭阈值作为频率的函数显著不同。在高频和低频上有显著性差异，而在中频上无统计学差异。在所有频率上，视觉前庭阈值与前庭阈值不同，尽管它们与视觉阈值没有显著差异。低频和高频下的前庭和视觉阈值显著不同，这支持了它们使用不同感知通路的事实。大脑可以通过整合前庭和视觉输入来确定在侧倾运动期间的空间中的身体运动。运动的组合估计优于前庭输入，但并不明显优于单独的视觉提示。这项研究可能是有用的工作了眩晕性疾病的前庭和视觉线索的整合受损（晕动病和偏头痛头晕）。
Visual and vestibular cues provide different information about spatial orientation. A previous study we performed showed that visual and vestibular cues are fused when the brain judges the roll-tilt direction. However it was unclear if the motion perception threshold measured in visual-vestibular conditions will be better than visual or vestibular thresholds at high frequencies. An innovative method of vestibular evaluation - the measurement of vestibular thresholds, was used. This sensitive test may represent a promising clinical tool in the evaluation and the treatment of vestibular and other equilibrium disorders. We used a Moog mobile platform with dedicated software. Four subjects were tested at 1, 2, 3, 4 and 5 Hz with adaptively decreasing amplitude. Subjects were asked to indicate the direction of motion in 3 conditions: vestibular only – subjects roll tilted in the dark, visual only – a visual scene was tilted in front of subjects, and combined visual - vestibular – subjects rotated while watching a stationary visual scene. Visual and vestibular thresholds significantly differed as a function of frequency. They were significantly different at high and low frequencies, while not statistically different at intermediate frequencies. Across all frequencies, the visual-vestibular thresholds are different from vestibular thresholds, although they do not differ significantly from visual thresholds. Vestibular and visual thresholds at low and high frequencies are significantly different which support the fact that they use different perception pathways. The brain may determine the body motion in space during roll tilt motion by integrating vestibular and visual inputs. The combined estimate of motion is better than the vestibular input and is not significantly better than the visual cues alone. This research may be useful in work-up of vertiginous disorders with impaired integration of vestibular and visual cues (motion-sickness and migraine dizziness).