Preparation of a molecularly imprinted polymer containing Europium(III) ions for luminescent sensing
Preparation of a molecularly imprinted polymer containing Europium(III) ions for luminescent sensing
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DOI：
10.1002/pola.26314
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发表时间：
2012-12
期刊：
影响因子：
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通讯作者：
Hyungwoo Kim;Youngdo Kim;J. Chang
中科院分区：
文献类型：
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作者：
Hyungwoo Kim;Youngdo Kim;J. Chang
引言镧系元素（III）离子在传感器应用中吸引了极大的兴趣，由于其独特的物理性质。它们的荧光来自于组态内的ff跃迁，发光范围窄，持续时间长，并且对配位环境敏感，这使它们成为一种很有希望的信号转换器。由于镧系元素（III）离子具有非常低的摩尔吸光系数，因此难以通过直接激发来填充其共振能级。作为替代方案，经由有机基天线间接激发镧系元素（III）离子被广泛用于获得强发光。位于镧系元素（III）离子周围的有机配体吸收光并通过分子内能量转移使镧系元素（III）离子敏化。1分子印迹是制备人工受体的一种实用方法。在分子印迹过程中，官能乙烯基单体和模板的复合物与交联剂共聚，随后从聚合基质中除去模板产生结合腔。2-8在分子印迹聚合物的传感器应用中，结合的分子通常通过间接方法如色谱法来分析。然而，该方法具有需要额外的分离过程的缺点。已经开发了几种直接传感方法，包括通过使用量子点10，11染料12，13和荧光聚合物14作为探针来检测分子结合9时光学性质的变化。还报道了使用镧系元素（III）离子来发出检测信号。15-19在这些研究中，传感器被设计为检测有机膦酸酯和有机磷酸酯，其对铕（III）离子具有强结合亲和力。印迹聚合物基质含有铕（III）离子和敏化发色团部分。一旦靶分子通过配位与离子结合，观察到发光强度增加，而不管它们的结构如何。这
INTRODUCTION The lanthanide (III) ions have attracted great interests in sensor applications due to their unique photophysical properties. Their luminescence resulting from intraconfigurational ff transition is narrow, long-lasting, and sensitive to the coordination environments, which makes them a promising candidate for signal transducers. Since the lanthanide (III) ions have very low molar absorptivities, it is difficult to populate their resonance levels by direct excitation. As an alternative, indirect excitation of the lanthanide (III) ions via an organic-based antenna is widely used to obtain strong luminescence. The organic ligands located around the lanthanide (III) ions absorb light and sensitize the lanthanide (III) ions by intramolecular energy transfer. 1Molecular imprinting is a practical method for preparing artificial receptors. In the molecular imprinting process, a complex of a functional vinyl monomer and a template is copolymerized with a crosslinking agent and subsequent removal of the template from the polymerized matrix generates binding cavities. 2–8 In sensor applications of molecularly imprinted polymers, the bound molecules are usually analyzed by an indirect method such as choromatography. 2, 3 However, this method has a drawback such that an additional separation process is required. Several direct sensing methods have been developed, involving the detection of changes in optical properties upon molecular binding9 by using quantum dots, 10, 11 dyes, 12, 13 and fluorescent polymers14 as probes. The use of the lanthanide (III) ions to signal the detection has also been reported. 15–19 In these studies, the sensors were designed to detect organophosphonates and organophosphates, which have strong binding affinity for europium (III) ions. The imprinted polymer matrices contained both the europium (III) ions and the sensitizing chromophore moieties. Once the target molecules were bound to the ions by coordination, there was observed an increase of luminescence intensity, regardless of their structures. This